Publications

Last 15 CNLab publications:

1. Development of a New Vaccine Adjuvant System Based on the Combination of the Synthetic TLR4 Agonist FP20 and a Synthetic QS-21 Variant Shaik M., Pasco S, Romerio A, Pifferi C, Sesana S, Re F, Bezuidenhout CX, Bracco S, Fernandez-Tejada A, Anguita J, Peri F Journal of Medicinal Chemistry, 2024 67 (24), pp. 22254 - 22262,  DOI: 10.1021/acs.jmedchem.4c02392

2. Nanoparticle shape is the game-changer for blood-brain barrier crossing and delivery through tunneling nanotubes among glioblastoma cells Sierri G, Saenz-De-Santa-Maria I, Renda A, Koch M, Sommi P, Anselmi-Tamburini U, Mauri M, D'Aloia A, Ceriani M, Salerno D, Mantegazza F, Zurzolo C, Re F Nanoscale, 2024 17 (2), pp. 992 - 1006, DOI: 10.1039/d4nr03174a

3. Nanostructured lipid carrier formulation for delivering poorly water-soluble ITF3756 HDAC inhibitor, Kravicz M, Taiarol L, Viegas JSR, Sierri G, Mauri M, Koch M, Steinkühler C, Re F, Journal of Drug Delivery Science and Technology, 2024, Volume 101, Part A, 106238, https://doi.org/10.1016/j.jddst.2024.106238.

4. A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy Amenta A,  Comi S, Kravicz M, Sesana S, Antoniou A, Passarella D, Seneci P, Pellegrino S, Re RSC Med. Chem., 2025, 16, 168 https://doi.org/10.1039/D4MD00517A 

5. Targeting specific brain districts for advanced nanotherapies: A review from the perspective of precision nanomedicine. Sierri, G., Patrucco, M., Ferrario, D., Renda, A., Comi, S., Ciprandi, M., Fontanini, V., Sica, F. S., Sesana, S., Costa Verdugo, M., Kravicz, M., Salassa, L., Busnelli, M., & Re, F. WIREs Nanomedicine and Nanobiotechnology, 2024, 16(5), e1991. https://doi.org/10.1002/wnan.1991 

6. New ALKBH2 and ALKBH5 inhibitors for treating glioblastoma Rivara M, Nicolini G, Malacrida A, Re F, Incerti M, Russo G, Zuliani V, Chemistry 9 2024 1016452024, https://doi.org/10.1016/j.rechem.2024.101645 

7. In Vitro Biocompatibility and Endothelial Permeability of Branched Polyglycidols Generated by Ring-Opening Polymerization of Glycidol with B(C6F5)3 under Dry and Wet Conditions Pagnacco CA, Kravicz MH, Sica FS, Fontanini V, González de San Román E, Lund R, Re F, Barroso-Bujans F Biomacromolecules  2024, 25, 6, 3583-3595 (Article) DOI: 10.1021/acs.biomac.4c00210

8. Biodegradable SPI-based hydrogel for controlled release of nanomedicines: A potential approach against brain tumors recurrence Viale F, Ciprandi M, Leoni L, Sierri G, Renda A, Barbugian F, Koch M, Sesana S, Salvioni L, Colombo M, Mantegazza F, Russo L, Re F Journal of Drug Delivery Science and Technology Volume 96, June 2024, 105672 https://doi.org/10.1016/j.jddst.2024.105672

9. Editorial: Molecular profiles of tunneling nanotubes (TNTs) in human diseases-from 2D cultures to complex tissue Resnik N, Levallet G, Errede M, Re F, Virgintino D,  Front. Cell Dev. Biol., 14 August 2024 Sec. Membrane Traffic and Organelle Dynamics Volume 12 - 2024 | https://doi.org/10.3389/fcell.2024.1461453

10. Nanoparticle’s Shape Is the Game-Changer for a Customized Delivery through Tunneling Nanotubes among Glioblastoma Cells Sierri G, Saenz-De-santa-maria I, Renda A, Sommi P, Koch M, Mauri M, Salerno D, Zurzolo C, Re F. 2024 Proceedings of the 9th World Congress on Recent Advances in Nanotechnology (RAN 2024) London, United Kingdom –April 8 – 10, 2024 Paper No. NDDTE 130 DOI: 10.11159/nddte24.130

11. Glibenclamide-Loaded Engineered Nanovectors (GNVs) Modulate Autophagy and NLRP3-Inflammasome Activation Saresella M, Zoia CP, La Rosa F, Bazzini C, Sala G, Grassenis E, Marventano I, Hernis A, Piancone F, Conti E, Sesana S, Re F, Seneci P, Ferrarese C, Clerici M. Pharmaceuticals, 2023 16 (12), art. no. 1725, DOI: 10.3390/ph16121725

12. Plasma and cerebrospinal fluid cholesterol esterification is hampered in Alzheimer’s disease  Turri M., Conti E., Pavanello C., Gastoldi F., Palumbo M., Bernini F., Aprea V., Re F., Barbiroli A., Emide D., Galimberti D., Tremolizzo L., Zimetti F., Calabresi L., Andreoni S., Appollonio I., Da Re F., Ferrarese C., Karantzoulis A., Negro G., Pozzi F.E., Remoli G., Storti B., Zoia C.P. Alzheimer's Research and Therapy, 2023 15 (1), art. no. 95, DOI: 10.1186/s13195-023-01241-6

13. Glibenclamide-Loaded Nanoparticles Reduce NLRP3 Inflammasome Activation and Modulate miR-223-3p/miR-7-1-5p Expression in THP-1 Cells Mancuso R., Citterio L.A., Agostini S., Marventano I., La Rosa F., Re F., Seneci P., Saresella M., Clerici M. Pharmaceuticals,  2023 16 (11), art. no. 1590 DOI: 10.3390/ph16111590

14. SPRi analysis of molecular interactions of mApoE-functionalized liposomes as drug delivery systems for brain diseases Picciolini S., Rodà F., Gualerzi A., Mangolini V., Forleo L., Mangolini A., Sesana S., Antoniou A., Re F., Seneci P., Bedoni M. Analyst, 2023 148 (23), pp. 6070 - 6077 DOI: 10.1039/d3an01507f 

15. Roadmap on nanomedicine for the central nervous system Ciofani G., Campisi M., Mattu C., Kamm R.D., Chiono V., Raynold A.A.M., Freitas J.S., Redolfi Riva E., Micera S., Pucci C., Novio F., Lorenzo J., Ruiz-Molina D., Sierri G., Re F., Wunderlich H., Kumari P., Kozielski K.L., Chami M., Marino A., Ferreira L. JPhys Materials, 2023 6 (2), art. no. 022501, DOI: 10.1088/2515-7639/acab88

16. Raman Spectroscopy Characterization of Multi-Functionalized Liposomes as Drug-Delivery Systems for Neurological Disorders Rodà F., Picciolini S., Mangolini V., Gualerzi A., Seneci P., Renda A., Sesana S., Re F., Bedoni M. Nanomaterials, 2023, 13 (4), art. no. 699, DOI: 10.3390/nano13040699

17. Editorial: Delivering nucleic acids to immune and non-immune cells Afonin K.A., Re F., Boraschi D. Frontiers in Immunology, 2023, 14, art. no. 1237506 DOI: 10.3389/fimmu.2023.1237506

18. Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity Re F., Giorgetti S., Biondi B., Scapin S., Mantegazza F., Cassina V., Sesana S.M., Rizzi L., Eberini I., Palazzolo L., Beeg M., Gobbi M., Sardina M., Masserini M. Annals of Medicine, 2023, 55 (1), art. no. 2205659, DOI: 10.1080/07853890.2023.2205659

19. Dual Functionalized Liposomes for Selective Delivery of Poorly Soluble Drugs to Inflamed Brain Regions Giofrè S., Renda A., Sesana S., Formicola B., Vergani B., Leone B.E., Denti V., Paglia G., Groppuso S., Romeo V., Muzio L., Balboni A., Menegon A., Antoniou A., Amenta A., Passarella D., Seneci P., Pellegrino S., Re F. Pharmaceutics, 2022, 14 (11), art. no. 2402, DOI: 10.3390/pharmaceutics14112402

20. Givinostat-Liposomes: Anti-Tumor Effect on 2D and 3D Glioblastoma Models and Pharmacokinetics Taiarol L, Bigogno C, Sesana S, (…), Dondio G, Steinkühler C, Re F. CANCERS, 2022  vol. 14, 2978 doi: 10.3390/cancers14122978 

21. TCR-engineered iNKT cells induce robust antitumor response by dual targeting cancer and suppressive myeloid cells Delfanti G., Cortesi F., Perini A., (…), Sesana S., Re F., Shen H., Dellabona P., Casorati G. SCIENCE IMMUNOLOGY 2022  vol. 7, p.1-18, doi: 10.1126/sciimmunol.abn6563 

22. H-Ferritin nanoparticle-mediated delivery of antibodies across a BBB in vitro model for treatment of brain malignancies. Rizzuto MA, Dal Magro R, Barbieri L, Pandolfi L, Sguazzini-Viscontini A, Truffi M, Salvioni L, Corsi F, Colombo M, Re F, Prosperi D. Biomater Sci. 2021 Feb 5. doi: 10.1039/d0bm01726d.

23. Oxidative Stress Boosts the Uptake of Cerium Oxide Nanoparticles by Changing Brain Endothelium Microvilli Pattern. Dal Magro R, Vitali A, Fagioli S, Casu A, Falqui A, Formicola B, Taiarol L, Cassina V, Marrano CA, Mantegazza F, Anselmi-Tamburini U, Sommi P, Re F. Antioxidants (Basel). 2021 Feb 9;10(2):266. doi: 10.3390/antiox10020266.

24. Post-Translational Modification Analysis of VDAC1 in ALS-SOD1 Model Cells Reveals Specific Asparagine and Glutamine Deamidation. Pittalà MGG, Reina S, Cubisino SAM, Cucina A, Formicola B, Cunsolo V, Foti S, Saletti R, Messina A. Antioxidants (Basel). 2020 Dec 2;9(12):1218. doi: 10.3390/antiox9121218.

25. An update of nanoparticle-based approaches for glioblastoma multiforme immunotherapy. Taiarol L, Formicola B, Magro RD, Sesana S, Re F. Nanomedicine (Lond). 2020 Aug;15(19):1861-1871. doi: 10.2217/nnm-2020-0132.