GIULIA SIERRI

PhD student in Molecular and Traslational Medicine (DIMET Program) at CNLab from y 2021. Giulia Sierri received her master's degree in Medical Biotechnologies in 2021 at University of Milano-Bicocca. The research activity of G.S. is aimed to design different type of nanoparticles for the delivery of drugs to central nervous system and to evaluate their efficacy on in vitro and 3D cell model of glioblastoma multiforme. In particular, her PhD project is aimed to design and validate nanomedicines for drug delivery in brain cancer by exploiting intercellular structures, called tunneling nanotubes. The aim of the study is to understand which NPs’s shape is the most suitable to be transferred, in order to exploit tunneling nanotubes as potential avenue for delivering anti-cancer agents and facilitate the intercellular redistribution of drugs in close and far away cells. Her expertise includes cellular and molecular biology, in vitro assays, synthesis and characterization of lipid-based nanoparticles, set up of 3D cellular model, optical and confocal microscopy. She is author of two review articles and two papers and referee for some scientific journals.